Bison Knee Caps are sized for small to medium dogs. We recommend smaller dogs under 30# but not to say they aren't managed well by larger breeds. It depends on how your dog chews. These bones are similar to knuckles in how they "sand" down. With that said, don't be surprised when the bone is half of the size it originally was to start. Dogs love the 'meaty-ness' and the challenge it presents since it isn't easy to get a good angle on for easy destruction.